Finding Engineering-Linked Indicators (FELIX)

Program Manager

David Markowitz

Program Information


FELIX Logo Final72dpiThe Finding Engineering-Linked Indicators (FELIX) program seeks to develop new experimental and computational tools to detect engineered biological systems. The development of new biotechnologies is enabling the ability to engineer a diversity of biological systems, with potential benefits ranging from new vaccines and therapeutics to novel materials and improved agriculture. Of particular note are genome editing tools that are commonly used worldwide for a range of significant research and development efforts. These technologies have made biological engineering more accessible, more convenient, and less expensive. At the same time, these beneficial biotechnologies could result in the accidental or deliberate misuse of biological systems with unforeseen or uncontrolled consequences that may have adverse health, economic, or national security implications. The FELIX program aims to develop new tools and approaches to improve and augment detection capabilities to expedite appropriate responses to the presence of engineered organisms.

Performers (Prime Contractors)

Broad Institute, Inc.; Charles Stark Draper Laboratory, Inc.; Ginkgo Bioworks, Inc.; Harvard College; Noblis, Inc.; Raytheon BBN Technologies Corporation

Related Program(s)


COVID-19 Related Research


Research Area(s)

  • Biological detection
  • Systems biology
  • Synthetic biology
  • Genome editing
  • Bioinformatics
  • Evolutionary biology

Related Publications

To access FELIX program-related publications, please visit Google Scholar

Related Article(s)